Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10005252 | 0.88 | TSHR (0.44) | NPC1TSHRTHRBDGKACASP6 | |
| SCHEMBL26751170 | 0.83 | NPC1 (0.41) | NPC1TSHRDGKACASP6SLC22A6 | |
| SCHEMBL16214300 | 0.78 | THRB (0.34) | THRB | |
| SCHEMBL14701136 | 0.78 | THRB (0.34) | THRB | |
| SCHEMBL18828855 | 0.78 | DGKA (0.50) | NPC1TSHRDGKASLC22A6 | |
| Ammonia Solution, Strong SCHEMBL27661104 | 0.78 | DGKA (0.46) | NPC1TSHRDGKACASP6SLC22A6 | |
| SCHEMBL18828975 | 0.78 | DGKA (0.50) | NPC1TSHRDGKASLC22A6 | |
| SCHEMBL6377936 | 0.76 | NPC1 (0.38) | NPC1TSHRTHRBDGKACASP6 | |
| SCHEMBL1389328 | 0.76 | TSHR (0.52) | NPC1TSHRTHRBDGKACASP6 | |
| SCHEMBL2285951 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129445-B2 | Moisture activated latent curing adhesive or sealant | ETHICON, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20080039548-A1 | Moisture activated latent curing adhesive or sealant | ETHICON, INC. | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039548-A1 | Moisture activated latent curing adhesive or sealant | ICAM1, EHMT1, CDH1 | NPC1 4842/4885TSHR 4861/4885THRB 4722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.