Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703708 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL8578909 | 0.78 | TDP1 (0.53) | ALDH1A1MEN1KMT2AMAPTATM | |
| SCHEMBL7703705 | 0.73 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL1715729 | 0.72 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AMAPTATM | |
| SCHEMBL30767916 | 0.72 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AMAPTATM | |
| SCHEMBL8677467 | 0.72 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL11780117 | 0.68 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTATM | |
| SCHEMBL12415529 | 0.68 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2AATMNPSR1 | |
| SCHEMBL6141672 | 0.68 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL9260950 | 0.65 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362181-B1 | BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6177423-B1 | N-(HYDROXY OR PROTECTED HYDROXY)-BENZO(DE)ISOQUINOLINE-1,3-DIONE DERIVATIVES; BACTERIAL DNA GYRASE AND DNA TOPOISOMERASE INHIBITORS USEFUL FOR ANTIBACTERIAL AGENTS HAVING REDUCED DRUG RESISTANCE AND REDUCED SIDE EFFECTS | WARNER-LAMBERT COMPANY | 2001-01-23 | — | — | US | disclosed |