Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703708 | 0.85 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1TDP1CRHBP | |
| SCHEMBL7709358 | 0.81 | MAPT (0.40) | ALDH1A1KMT2AMEN1TDP1ATAD2 | |
| SCHEMBL7706801 | 0.73 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1TDP1MAPT | |
| SCHEMBL7706701 | 0.70 | MEN1 (0.47) | ALDH1A1KMT2AMEN1TDP1CRHBP | |
| SCHEMBL8578190 | 0.69 | TDP1 (0.44) | KMT2AMEN1TDP1MAPK1MAPT | |
| SCHEMBL7709710 | 0.68 | MEN1 (0.47) | ALDH1A1KMT2AMEN1TDP1CRHBP | |
| SCHEMBL7706698 | 0.64 | MAPT (0.44) | ALDH1A1KMT2AMEN1TDP1MAPK1 | |
| SCHEMBL7706710 | 0.62 | TYMS (0.45) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL7706707 | 0.58 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1TDP1MAPK1 | |
| SCHEMBL10776759 | 0.58 | CHRM1 (0.49) | ALDH1A1KMT2AMEN1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362181-B1 | BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6177423-B1 | N-(HYDROXY OR PROTECTED HYDROXY)-BENZO(DE)ISOQUINOLINE-1,3-DIONE DERIVATIVES; BACTERIAL DNA GYRASE AND DNA TOPOISOMERASE INHIBITORS USEFUL FOR ANTIBACTERIAL AGENTS HAVING REDUCED DRUG RESISTANCE AND REDUCED SIDE EFFECTS | WARNER-LAMBERT COMPANY | 2001-01-23 | — | — | US | disclosed |