Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 10/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6786478 | 0.82 | CYP2J2 (0.49) | HRH2HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL6780187 | 0.78 | HRH2 (0.73) | HRH2HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL7159651 | 0.78 | CCR2 (0.61) | HTR2ADRD2 | |
| SCHEMBL6780994 | 0.75 | HRH2 (0.73) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6785252 | 0.73 | HRH2 (0.60) | HRH2HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL11784884 | 0.72 | DRD2 (0.65) | HTR2AHTR2CHTR2BDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL11785189 | 0.72 | DRD2 (0.64) | HTR2AHTR2CHTR2BDRD2DRD4 | |
| SCHEMBL6784820 | 0.72 | KDM4E (0.48) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6780178 | 0.71 | HRH2 (0.58) | HRH2HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL6782119 | 0.71 | HRH2 (0.64) | HRH2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183251-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | Almirall Prodesfarma, S.A. (ES) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000075130-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA, S.A. (ES) | 2000-12-14 | — | — | WO | disclosed |