Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 5/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11786426 | 0.89 | ADRA1D (0.66) | CCR2ADRA1DSLC6A4DRD2 | |
| Hydrochloric Acid SCHEMBL11784755 | 0.88 | ADRA1D (0.67) | CCR2ADRA1DSLC6A4DRD2 | |
| SCHEMBL11784971 | 0.83 | DRD2 (0.70) | ADRA1DDRD2 | |
| SCHEMBL11788127 | 0.83 | CCR2 (0.72) | CCR2ADRA1DSLC6A4DRD2 | |
| Hydrochloric Acid SCHEMBL11784284 | 0.82 | CCR2 (0.70) | CCR2ADRA1DSLC6A4DRD2 | |
| Hydrochloric Acid SCHEMBL11789367 | 0.82 | DRD2 (0.69) | ADRA1DDRD2 | |
| SCHEMBL3380970 | 0.81 | SLC6A4 (0.71) | CCR2ADRA1DSLC6A4DRD2HTR2A | |
| SCHEMBL6779379 | 0.80 | CCR2 (0.58) | CCR2ADRA1DSLC6A4DRD2HTR2A | |
| SCHEMBL7481574 | 0.80 | HTR1D (0.52) | CCR2ADRA1DDRD2 | |
| SCHEMBL7706920 | 0.78 | HRH2 (0.49) | DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003501424-A | — | — | 2003-01-14 | — | — | JP | claimed |
| EP-1183251-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | Almirall Prodesfarma, S.A. (ES) | 2002-03-06 | — | — | EP | claimed |
| WO-2000075130-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA, S.A. (ES) | 2000-12-14 | — | — | WO | claimed |