Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | TDO2 | P48775 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6330057 | 0.89 | KCNH2 (0.46) | IDO1SLC6A2SLC6A4SLC6A3KCNH2 | |
| Hydrochloric Acid SCHEMBL4443325 | 0.86 | IDO1 (0.51) | IDO1TDO2ABCB1F2PRSS1 | |
| SCHEMBL9379292 | 0.84 | MMP12 (0.47) | IDO1TDO2ABCB1F2PRSS1 | |
| SCHEMBL28902075 | 0.83 | IDO1 (0.50) | IDO1TDO2F2PRSS1ACP3 | |
| SCHEMBL7796542 | 0.80 | IDO1 (0.47) | IDO1TDO2F2PRSS1ACP3 | |
| SCHEMBL1520876 | 0.80 | IDO1 (0.69) | IDO1TDO2F2PRSS1ACP3 | |
| SCHEMBL3481822 | 0.80 | IDO1 (0.47) | IDO1TDO2F2PRSS1ACP3 | |
| SCHEMBL3950653 | 0.80 | IDO1 (0.47) | IDO1TDO2F2PRSS1ACP3 | |
| SCHEMBL4056401 | 0.79 | SIGMAR1 (0.46) | ACP3SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL1098807 | 0.79 | AOC3 (0.43) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077959-A1 | MORPHOLINO ETHERS | Glaxo Wellcome S.A. (ES) | 2001-02-28 | — | — | EP | claimed |
| WO-1999058512-A1 | MORPHOLINO ETHERS | GLAXO WELLCOME S.A. (ES) | 1999-11-18 | — | — | WO | claimed |
| EP-2227233-B1 | IDO INHIBITORS | NEWLINK GENETICS (US) | 2013-02-13 | — | — | EP | disclosed |
| EP-1228049-A1 | ANTIFUNGAL SORDARICIN DERIVATIVES | Glaxo Wellcome S.A. (ES) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001034583-A1 | ANTIFUNGAL SORDARICIN DERIVATIVES | GLAXO WELLCOME SA (ES) | 2001-05-17 | — | — | WO | disclosed |
| EP-1077959-A1 | MORPHOLINO ETHERS | Glaxo Wellcome S.A. (ES) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058512-A1 | MORPHOLINO ETHERS | GLAXO WELLCOME S.A. (ES) | 1999-11-18 | — | — | WO | disclosed |