Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7707527 | 0.94 | ALDH1A1 (0.50) | HDAC1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7710323 | 0.89 | HDAC1 (0.54) | HDAC1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7707519 | 0.87 | ALDH1A1 (0.46) | HDAC1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7091717 | 0.86 | ALDH1A1 (0.45) | HDAC1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL6989433 | 0.86 | ROCK2 (0.52) | HDAC1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7707187 | 0.83 | ROCK2 (0.49) | HDAC1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7707537 | 0.83 | ROCK2 (0.48) | HDAC1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7092338 | 0.79 | EPHX2 (0.53) | ALDH1A1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL7707124 | 0.79 | SMN1; SMN2 (0.48) | HDAC1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7707516 | 0.79 | SMN1; SMN2 (0.46) | HDAC1ALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6353007-B1 | ANTIINFLAMMATORY AGENTS AND INHIBITORS OF CELLULAR POLIFERATION | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-03-05 | — | — | US | claimed |
| US-6353007-B1 | ANTIINFLAMMATORY AGENTS AND INHIBITORS OF CELLULAR POLIFERATION | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-03-05 | — | — | US | disclosed |