Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7707552 | 0.86 | LTB4R (0.31) | ITK | |
| SCHEMBL7242736 | 0.77 | CLK1 (0.36) | — | |
| SCHEMBL7088080 | 0.75 | MAPT (0.41) | — | |
| SCHEMBL7244223 | 0.74 | KDM4E (0.35) | — | |
| SCHEMBL6992299 | 0.73 | CACNA1B (0.42) | — | |
| SCHEMBL9171948 | 0.66 | TSHR (0.40) | — | |
| SCHEMBL6990601 | 0.65 | USP30 (0.31) | — | |
| SCHEMBL9040496 | 0.63 | ALDH1A1 (0.36) | — | |
| SCHEMBL6988003 | 0.62 | ALDH1A1 (0.52) | — | |
| Hydrochloric Acid SCHEMBL2730055 | 0.62 | LOXL2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303508-A1 | SUBSTITUTED 1-(4-AMINOPHENYL)INDOLES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | Boehringer Ingelheim Pharmaceuticals, Inc. (US) | 2003-04-23 | — | — | EP | disclosed |
| US-6353007-B1 | ANTIINFLAMMATORY AGENTS AND INHIBITORS OF CELLULAR POLIFERATION | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-03-05 | — | — | US | disclosed |
| WO-2002006273-A1 | SUBSTITUTED 1-(4-AMINOPHENYL)INDOLES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-01-24 | — | — | WO | disclosed |