Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | BMP1 | P13497 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702197 | 0.86 | RIPK1 (0.43) | HDAC6 | |
| SCHEMBL7705112 | 0.85 | STAT5B (0.46) | KMT2AHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7707821 | 0.84 | AKT1 (0.48) | ALDH1A1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL12550044 | 0.84 | STAT5B (0.49) | KMT2AMEN1ALDH1A1BMP1MTOR | |
| SCHEMBL7705341 | 0.83 | TSHR (0.40) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6338886 | 0.83 | TAS2R14 (0.42) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL5018764 | 0.79 | LSS (0.44) | KMT2AMEN1LSSBMP1MTOR | |
| SCHEMBL2056134 | 0.78 | HDAC3 (0.49) | KMT2AMEN1LSSMTORPPARG | |
| SCHEMBL1857874 | 0.77 | HDAC3 (0.55) | KMT2AMEN1ALDH1A1LSSPPARG | |
| SCHEMBL30027626 | 0.76 | TSHR (0.39) | HDAC3HDAC1HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355665-B1 | ANTIHISTAMINES, ANTIALLERGENS AND IRRITABLE BOWEL SYNDROME. | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-03-12 | — | — | US | disclosed |