SCHEMBL7707848

SCHEMBL7707848

Cc1ccc(NC(=O)C23CC4CC(CC(C4)C2)C3)cc1

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.65
CA9 Q16790 2/20 0.64
CA12 O43570 1/20 0.64
SMN1; SMN2 Q16637 3/20 0.60
LMNA P02545 2/20 0.60
STS P08842 1/20 0.59
MAPT P10636 1/20 0.59
ALDH1A1 P00352 4/20 0.57
TSHR P16473 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
P2RX7 Q99572 3/20 0.55
POLB P06746 1/20 0.55
ENPP3 O14638 1/20 0.54
CA2 P00918 1/20 0.54
ENPP1 P22413 1/20 0.54
ENPP2 Q13822 1/20 0.54
EPHX2 P34913 1/20 0.54
P2RX2 Q9UBL9 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3324612 0.87 ALDH1A1 (0.70) CNR2CA9CA12SMN1; SMN2STS
SCHEMBL1549023 0.85 P2RX7 (0.73) CNR2CA9CA12SMN1; SMN2STS
SCHEMBL12443631 0.84 CNR2 (0.70) CNR2CA9CA12SMN1; SMN2STS
SCHEMBL5923504 0.84 P2RX7 (0.73) CNR2MAPTALDH1A1P2RX7
SCHEMBL8303597 0.83 P2RX7 (0.72) CNR2CA9CA12SMN1; SMN2STS
SCHEMBL5811901 0.83 CA9 (0.68) CNR2CA9CA12SMN1; SMN2STS
SCHEMBL3321310 0.83 CA9 (0.64) CNR2CA9CA12SMN1; SMN2STS
SCHEMBL7705995 0.83 P2RX7 (0.71) CNR2CA9CA12SMN1; SMN2LMNA
SCHEMBL1167370 0.83 P2RX2 (0.76) CNR2CA9CA12SMN1; SMN2LMNA
SCHEMBL4609462 0.81 EPHX2 (0.67) CNR2CA9CA12LMNASTS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6348625-B1 TREATING CORRESPONDING CARBOXYLIC ACID FUNCTIONAL GROUP WITH N,N-DIETHYL-1,1,2,3,3,3-HEXAFLUOROPROPYLAMINE FOLLOWED BY AMMONIA ANDERSON GLORIA LONG (US) 2002-02-19 US claimed
US-7220532-B2 Chemical amplification type resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-22 US disclosed
US-7220532-B2 Chemical amplification type resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-22 US disclosed
US-6348625-B1 TREATING CORRESPONDING CARBOXYLIC ACID FUNCTIONAL GROUP WITH N,N-DIETHYL-1,1,2,3,3,3-HEXAFLUOROPROPYLAMINE FOLLOWED BY AMMONIA ANDERSON GLORIA LONG (US) 2002-02-19 US disclosed