Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.71 |
| ▸ | CA9 | Q16790 | 2/20 | 0.64 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.64 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | CNR2 | P34972 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | STS | P08842 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31552469 | 0.93 | P2RX7 (0.60) | P2RX7CA9ENPP3CA2ENPP1 | |
| SCHEMBL19072437 | 0.89 | P2RX7 (0.57) | P2RX7CA9ENPP3CA2ENPP1 | |
| SCHEMBL28424952 | 0.84 | P2RX7 (0.52) | P2RX7CA9ENPP3CA2ENPP1 | |
| SCHEMBL25447578 | 0.84 | P2RX7 (0.77) | P2RX7NPSR1EPHX2CYP2D6MAPT | |
| SCHEMBL1549023 | 0.84 | P2RX7 (0.73) | P2RX7CA9ENPP3CA2ENPP1 | |
| SCHEMBL1947902 | 0.83 | SMN1; SMN2 (0.66) | P2RX7CA9ENPP3CA2ENPP1 | |
| SCHEMBL5092145 | 0.83 | P2RX7 (0.67) | P2RX7MEN1KMT2ASMN1; SMN2EPHX2 | |
| SCHEMBL7827905 | 0.83 | EPHX2 (0.67) | P2RX7CA9CA12MEN1KMT2A | |
| SCHEMBL8303597 | 0.83 | P2RX7 (0.72) | P2RX7CA9ENPP3CA2ENPP1 | |
| SCHEMBL3321310 | 0.83 | CA9 (0.64) | P2RX7CA9ENPP3CA2ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170283347-A1 | NOVEL ADAMANTANE DERIVATIVE COMPOUND | AMOREPACIFIC CORPORATION (KR) | 2017-10-05 | — | — | US | claimed |
| CN-107207416-A | Novel adamantine alkane derivatives compound | 株式会社爱茉莉太平洋 | 2017-09-26 | — | — | CN | claimed |
| EP-3187486-A1 | NOVEL ADAMANTANE DERIVATIVE COMPOUND | Amorepacific Corporation (KR) | 2017-07-05 | — | — | EP | claimed |
| US-6348625-B1 | TREATING CORRESPONDING CARBOXYLIC ACID FUNCTIONAL GROUP WITH N,N-DIETHYL-1,1,2,3,3,3-HEXAFLUOROPROPYLAMINE FOLLOWED BY AMMONIA | ANDERSON GLORIA LONG (US) | 2002-02-19 | — | — | US | claimed |
| US-12240857-B2 | Adamantane derivatives for the treatment of filovirus infection | ARISAN THERAPEUTICS INC. (US) | 2025-03-04 | — | — | US | disclosed |
| EP-3187486-B1 | NOVEL ADAMANTANE DERIVATIVE COMPOUND | AMOREPACIFIC CORP (KR) | 2023-10-18 | — | — | EP | disclosed |
| CN-115556446-A | Decorative film and method for producing decorative molded body using same | 日本聚丙烯株式会社 | 2023-01-03 | — | — | CN | disclosed |
| CN-115556441-A | Decorative film and method for producing decorative molded body using same | 日本聚丙烯株式会社 | 2023-01-03 | — | — | CN | disclosed |
| CN-111386185-A | Decorative film and method for producing decorative molded body using same | 日本聚丙烯株式会社 | 2020-07-07 | — | — | CN | disclosed |
| US-10696611-B2 | Adamantane derivative compound | AMOREPACIFIC CORPORATION (KR) | 2020-06-30 | — | — | US | disclosed |
| US-10696611-B2 | Adamantane derivative compound | AMOREPACIFIC CORPORATION (KR) | 2020-06-30 | — | — | US | disclosed |
| CN-107207416-B | Novel adamantane derivative compound | 株式会社爱茉莉太平洋 | 2020-02-07 | — | — | CN | disclosed |
| WO-2017127306-A1 | ADAMATANE DERIVATIVES FOR THE TREATMENT OF FILOVIRUS INFECTION | ARISAN THERAPEUTICS (US) | 2017-07-27 | — | — | WO | disclosed |
| EP-3187486-A1 | NOVEL ADAMANTANE DERIVATIVE COMPOUND | Amorepacific Corporation (KR) | 2017-07-05 | — | — | EP | disclosed |
| EP-3187486-A1 | NOVEL ADAMANTANE DERIVATIVE COMPOUND | Amorepacific Corporation (KR) | 2017-07-05 | — | — | EP | disclosed |
| US-7220532-B2 | Chemical amplification type resist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-22 | — | — | US | disclosed |
| US-7220532-B2 | Chemical amplification type resist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-22 | — | — | US | disclosed |
| US-6348625-B1 | TREATING CORRESPONDING CARBOXYLIC ACID FUNCTIONAL GROUP WITH N,N-DIETHYL-1,1,2,3,3,3-HEXAFLUOROPROPYLAMINE FOLLOWED BY AMMONIA | ANDERSON GLORIA LONG (US) | 2002-02-19 | — | — | US | disclosed |
| US-4053509-A | ADAMANTANE-CARBOXAMIDES OR CYCLOPROPANE-CARBOXAMIDES, CNS DRUGS ON | SCHERING CORPORATION (US) | 1977-10-11 | — | — | US | disclosed |
| US-3944675-A | Substituted aryl and aralkyl amides in the treatment of parkinsonism | SCHERING CORPORATION (US) | 1976-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12240857-B2 | Adamantane derivatives for the treatment of filovirus infection | IFNAR1, MEP1B, MEP1A | P2RX7 1347/4885CA9 4751/4885ENPP3 1037/4885 |
| US-10696611-B2 | Adamantane derivative compound | ADAM8, BACE1, CYP17A1 | P2RX7 2139/4885CA9 623/4885ENPP3 1563/4885 |
| US-20170283347-A1 | NOVEL ADAMANTANE DERIVATIVE COMPOUND | ADAM8, CYP17A1, ADAM10 | P2RX7 2069/4885CA9 758/4885ENPP3 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.