Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 3/20 | 0.42 |
| ▸ | MC5R | P33032 | 3/20 | 0.42 |
| ▸ | MC3R | P41968 | 3/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7704806 | 1.00 | CTSC (0.44) | CTSCALDH1A1MEN1KMT2AMC4R | |
| SCHEMBL7702120 | 1.00 | CTSC (0.44) | CTSCALDH1A1MEN1KMT2AMC4R | |
| SCHEMBL7710700 | 0.87 | HTR2C (0.51) | KMT2AHDAC1SMN1; SMN2CCR5KCNH2 | |
| SCHEMBL7704731 | 0.87 | HTR2C (0.51) | KMT2AHDAC1SMN1; SMN2CCR5KCNH2 | |
| SCHEMBL7704744 | 0.74 | PRCP (0.41) | — | |
| SCHEMBL7702119 | 0.74 | HTR2C (0.49) | KMT2AHDAC1SMN1; SMN2CCR5KCNH2 | |
| SCHEMBL7707952 | 0.73 | SIGMAR1 (0.42) | MC4RMC5RMC3R | |
| SCHEMBL7707925 | 0.73 | SIGMAR1 (0.42) | MC4RMC5RMC3R | |
| SCHEMBL194737 | 0.73 | SCN4A (0.43) | CTSCALDH1A1HDAC1HTR2CSCN4A | |
| SCHEMBL6970522 | 0.73 | POLB (0.43) | CTSCALDH1A1HTR2CSCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263730-A1 | AMINE DERIVATIVES FOR THE TREATMENT OF APOPTOSIS | Applied Research Systems ARS Holding N.V. (AN) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001060798-A1 | AMINE DERIVATIVES FOR THE TREATMENT OF APOPTOSIS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-08-23 | — | — | WO | disclosed |