Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 15/20 | 0.42 |
| ▸ | HTR2A | P28223 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 11/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29274083 | 0.84 | — | — | |
| SCHEMBL29741313 | 0.80 | GRM5 (0.35) | ALDH1A1 | |
| SCHEMBL5111384 | 0.80 | NPC1 (0.37) | ALDH1A1KDM4EMEN1CYP1A2CYP3A4 | |
| SCHEMBL23793110 | 0.80 | GRM5 (0.35) | ALDH1A1 | |
| SCHEMBL30932851 | 0.75 | HTR2C (0.35) | HTR2CHTR2AHTR2BHTR3ACHRM4 | |
| SCHEMBL8057128 | 0.75 | HTR2C (0.35) | HTR2CHTR2AHTR2BHTR3ACHRM4 | |
| SCHEMBL13180692 | 0.73 | NNMT (0.39) | HTR2CHTR2AALDH1A1KDM4EMEN1 | |
| Bromide SCHEMBL11076585 | 0.73 | HTR2C (0.34) | HTR2CHTR2AHTR2BHTR3ACHRM4 | |
| SCHEMBL13217226 | 0.73 | NNMT (0.36) | HTR2CHTR2AALDH1A1KDM4EMEN1 | |
| SCHEMBL24638722 | 0.71 | CHRNB2 (0.42) | HTR2CHTR2AHTR2BHTR3ACHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240182480-A1 | 5-HT2A AND/OR 5-HT2C RECEPTOR AGONISTS | DIAMOND THERAPEUTICS INC. (CA) | 2024-06-06 | — | — | US | disclosed |
| WO-2022234339-A2 | 5-HT2A AND/OR 5-HT2C RECEPTOR AGONISTS | DIAMOND THERAPEUTICS INC. (CA) | 2022-11-10 | — | — | WO | disclosed |
| WO-2011124524-A1 | COMBINATIONS OF MEDICAMENTS, CONTAINING PDE4 INHIBITORS AND EP4 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-10-13 | — | — | WO | disclosed |
| WO-2010097332-A1 | DRUG COMBINATIONS CONTAINING PDE4 INHIBITORS AND NSAIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240182480-A1 | 5-HT2A AND/OR 5-HT2C RECEPTOR AGONISTS | HTR2C, HTR2A, HTR5A | HTR2C 1/4885HTR2A 2/4885ALDH1A1 2161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.