SCHEMBL7708151

SCHEMBL7708151

COc1cc[c]c(-c2ccc(Cl)cc2)c1-c1ccc(Cl)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 1/20 0.38
MAPT P10636 2/20 0.35
MAPK1 P28482 2/20 0.35
HTT P42858 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
KDM4E B2RXH2 1/20 0.35
S1PR4 O95977 1/20 0.35
HSP90AA1 P07900 1/20 0.35
G6PD P11413 1/20 0.35
S1PR1 P21453 1/20 0.35
OPRK1 P41145 1/20 0.35
RAB9A P51151 1/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
MCL1 Q07820 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
TLR9 Q9NR96 1/20 0.35
ERN1 O75460 1/20 0.35
TP53 P04637 2/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11802233 0.94 CYP1A2 (0.41) CRHR1KDM4ELMNAMEN1KMT2A
SCHEMBL7705602 0.84 ACHE (0.35) MAPTMAPK1KDM4ERAB9ALMNA
SCHEMBL7711577 0.83 MEN1 (0.30) MAPTTP53MDM2MEN1KMT2A
SCHEMBL7702832 0.83 MGAM (0.46) HSP90AA1ERN1GAA
SCHEMBL7071376 0.82 PDE4B (0.39) MAPTKDM4ERAB9ALMNAMEN1
SCHEMBL7705593 0.80 TDO2 (0.35) MAPTMAPK1NPSR1HSP90AA1RAB9A
SCHEMBL7702845 0.80 PDGFRB (0.38) MAPTMAPK1HTTNPSR1KDM4E
SCHEMBL7707636 0.78 ABCB1 (0.32)
SCHEMBL10415602 0.78 TSHR (0.40) MAPTTP53TSHRMEN1KMT2A
SCHEMBL28621595 0.77 ALDH1A1 (0.38) MAPTRAB9AERN1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6358665-B1 ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE CLARIANT INTERNATIONAL LTD. (CH) 2002-03-19 US disclosed
EP-1033624-A1 RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE Clariant International Ltd. (CH) 2000-09-06 EP disclosed