SCHEMBL7708200

SCHEMBL7708200

[CH2]CC[CH]c1ccc(Cl)cc1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.48
LMNA P02545 1/20 0.38
CYP2A6 P11509 1/20 0.38
AHR P35869 1/20 0.38
MAOB P27338 1/20 0.38
CYP1A2 P05177 1/20 0.35
FBP1 P09467 2/20 0.33
TSHR P16473 1/20 0.33
GRIN2D O15399 2/20 0.32
GRIN3B O60391 2/20 0.32
GRIN1 Q05586 2/20 0.32
GRIN2A Q12879 2/20 0.32
GRIN2B Q13224 2/20 0.32
GRIN2C Q14957 2/20 0.32
GRIN3A Q8TCU5 2/20 0.32
HTT P42858 1/20 0.32
IDO1 P14902 1/20 0.32
G6PC1 P35575 1/20 0.32
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11050322 0.87 ALDH1A1 (0.35)
SCHEMBL7708213 0.86 HSD17B10 (0.44) HSD17B10LMNACYP2A6AHRMAOB
SCHEMBL7803552 0.80 HSD17B10 (0.52) HSD17B10LMNACYP2A6AHRMAOB
SCHEMBL2089771 0.77 AHR (0.45) HSD17B10AHRCYP1A2FBP1
SCHEMBL2089772 0.77 AHR (0.45) HSD17B10AHRCYP1A2FBP1
SCHEMBL293565 0.76 HSD17B10 (0.48) HSD17B10LMNACYP2A6AHRMAOB
SCHEMBL4995492 0.76 HSD17B10 (0.48) HSD17B10LMNACYP2A6AHRMAOB
SCHEMBL5469370 0.76 CYP2A6 (0.48) CYP2A6FBP1GRIN2DGRIN3BGRIN1
SCHEMBL7702901 0.76 ALDH5A1 (0.48) HSD17B10LMNAMAOBCYP1A2HTT
SCHEMBL4997007 0.76 HSD17B10 (0.48) HSD17B10LMNACYP2A6AHRMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1159623-C Radiation-sensitive compsn. of chemical amplification type containing onium salt type photosensitive acid generating agent 克拉瑞特金融(BVI)有限公司 2004-07-28 CN disclosed
US-6358665-B1 ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE CLARIANT INTERNATIONAL LTD. (CH) 2002-03-19 US disclosed
CN-1274433-A Radiation-sensitive compsn. of chemical amplification type containing onium salt type photosensitive acid generating agent CLARIANT INT LTD (CH) 2000-11-22 CN disclosed
EP-1033624-A1 RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE Clariant International Ltd. (CH) 2000-09-06 EP disclosed