SCHEMBL7803552

SCHEMBL7803552

[CH2]C[CH]c1ccc(Cl)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.52
LMNA P02545 1/20 0.42
CYP2A6 P11509 1/20 0.42
AHR P35869 1/20 0.41
MAOB P27338 1/20 0.41
CYP1A2 P05177 1/20 0.38
MEN1 O00255 1/20 0.36
MAPK1 P28482 1/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
FBP1 P09467 2/20 0.35
IDO1 P14902 1/20 0.35
GRIN2D O15399 2/20 0.34
GRIN3B O60391 2/20 0.34
GRIN1 Q05586 2/20 0.34
GRIN2A Q12879 2/20 0.34
GRIN2B Q13224 2/20 0.34
GRIN2C Q14957 2/20 0.34
GRIN3A Q8TCU5 2/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7708200 0.80 HSD17B10 (0.48) HSD17B10LMNACYP2A6AHRMAOB
SCHEMBL7708213 0.77 HSD17B10 (0.44) HSD17B10LMNACYP2A6AHRMAOB
SCHEMBL7575672 0.76 HSD17B10 (0.55) HSD17B10LMNACYP2A6AHRMAOB
SCHEMBL1609713 0.76 HSD17B10 (0.55) HSD17B10LMNACYP2A6AHRMAOB
SCHEMBL2092199 0.75 AHR (0.48) HSD17B10LMNACYP2A6AHRMAOB
SCHEMBL7207019 0.75 AHR (0.48) HSD17B10LMNACYP2A6AHRMAOB
SCHEMBL2092197 0.75 AHR (0.48) HSD17B10LMNACYP2A6AHRMAOB
SCHEMBL7795364 0.74 CYP2A6 (0.52) CYP2A6MEN1KMT2AL3MBTL1FBP1
SCHEMBL7801924 0.74 ALDH5A1 (0.52) HSD17B10LMNAMAOBCYP1A2MEN1
SCHEMBL11144431 0.74 APP (0.37) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2784072-A1 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES Bayer CropScience AG (DE) 2014-10-01 EP disclosed
EP-2784071-A1 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES Bayer CropScience AG (DE) 2014-10-01 EP disclosed
EP-1070703-A1 Cyclobutene derivatives Sankyo Company Limited (JP) 2001-01-24 EP disclosed
US-4405757-A Macromolecular complexes of amidocarbonylic water-soluble polymers and square planar platinous and equivalent organometallics HOWELL BOBBY A 1983-09-20 US disclosed
US-4140514-A HERBICIDES CHEVRON RESEARCH COMPANY (US) 1979-02-20 US disclosed