Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | LDHB | P07195 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708493 | 1.00 | LMNA (0.56) | LMNAHSD17B10ALDH1A1RAB9ASMN1; SMN2 | |
| Benzophenone SCHEMBL27761907 | 0.94 | LMNA (0.57) | LMNAHSD17B10ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL65737 | 0.86 | LMNA (0.59) | LMNAHSD17B10ALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL67237 | 0.86 | LMNA (0.59) | LMNAHSD17B10ALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL1715 | 0.86 | LMNA (0.59) | LMNAHSD17B10ALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL29757088 | 0.86 | LMNA (0.59) | LMNAHSD17B10ALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL20769804 | 0.86 | LMNA (0.59) | LMNAHSD17B10ALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL1574429 | 0.86 | AKR1C3 (0.58) | LMNAHSD17B10ALDH1A1HTR1AADRA1A | |
| SCHEMBL11704231 | 0.86 | AKR1C3 (0.57) | LMNAHSD17B10ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8680665 | 0.85 | AKR1C3 (0.58) | LMNAHSD17B10ALDH1A1RAB9AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365398-B1 | REACTING RACEMIC CARBOXYLIC ACID ESTER WITH RACEMIC ALCOHOL IN PRESENCE OF A CARBOXYL ESTER HYDROLASE | BASF AKTIENGESELLSCHAFT (DE) | 2002-04-02 | — | — | US | disclosed |