Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5492443 | 0.86 | S1PR4 (0.41) | BCHES1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL5492439 | 0.86 | S1PR4 (0.41) | BCHES1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL28319178 | 0.84 | CTSK (0.46) | — | |
| SCHEMBL5495309 | 0.79 | S1PR1 (0.51) | S1PR4S1PR1S1PR3S1PR5RARB | |
| SCHEMBL5495307 | 0.79 | S1PR1 (0.51) | S1PR4S1PR1S1PR3S1PR5RARB | |
| SCHEMBL5492435 | 0.77 | S1PR1 (0.37) | S1PR4S1PR1S1PR3S1PR5RARB | |
| SCHEMBL18568181 | 0.77 | CTSK (0.45) | — | |
| SCHEMBL18956285 | 0.77 | L3MBTL1 (0.44) | MEN1KMT2ABCHE | |
| SCHEMBL18956284 | 0.77 | L3MBTL1 (0.44) | MEN1KMT2ABCHE | |
| SCHEMBL18956288 | 0.72 | REN (0.38) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1251827-A2 | NASALLY ADMINISTRABLE CYCLIC PEPTIDE COMPOSITIONS | Basilea Pharmaceutica AG (CH) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001052894-A2 | NASALLY ADMINISTRABLE CYCLIC PEPTIDE COMPOSITIONS | BASILEA PHARMACEUTICA AG (CH) | 2001-07-26 | — | — | WO | disclosed |