Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | CALML3 | P27482 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SDHA | P31040 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708542 | 1.00 | MAOA (0.46) | MAOAGPR119USP30MAOBCALML3 | |
| SCHEMBL6402350 | 0.93 | CALML3 (0.48) | MAOAGPR119USP30MAOBCALML3 | |
| SCHEMBL6402349 | 0.93 | CALML3 (0.48) | MAOAGPR119USP30MAOBCALML3 | |
| SCHEMBL6395268 | 0.90 | MAOA (0.49) | MAOAGPR119USP30MAOBCALML3 | |
| SCHEMBL6395262 | 0.90 | MAOA (0.49) | MAOAGPR119USP30MAOBCALML3 | |
| SCHEMBL7971517 | 0.87 | MAOA (0.59) | MAOAGPR119MAOBCALML3LMNA | |
| SCHEMBL7971520 | 0.87 | MAOA (0.59) | MAOAGPR119MAOBCALML3LMNA | |
| SCHEMBL6402366 | 0.86 | GPR119 (0.51) | MAOAGPR119USP30MAOBCALML3 | |
| SCHEMBL6402364 | 0.86 | GPR119 (0.51) | MAOAGPR119USP30MAOBCALML3 | |
| SCHEMBL6398572 | 0.84 | MAOB (0.49) | MAOAMAOBCALML3LMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358942-B1 | MICROBIOCIDES AND BACTERICIDES FOR TREATING GRAMPOSITIVE, BACTEROIDES, CLOSTRIDIUM, MYCOBACTERIUM, STAPHYLOCOCCUS AND STREPTOCOCCUS INFECTIONS | PHARMACIA & UPJOHN COMPANY | 2002-03-19 | — | — | US | disclosed |