SCHEMBL7708625

SCHEMBL7708625

[CH2]CC[CH]c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.38
MAOB P27338 3/20 0.38
SLC6A4 P31645 1/20 0.37
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.36
CHRNA7 P36544 1/20 0.35
HTR2C P28335 1/20 0.33
HTR6 P50406 1/20 0.33
MMP3 P08254 1/20 0.33
MMP8 P22894 1/20 0.33
MMP13 P45452 1/20 0.33
MAPK1 P28482 1/20 0.32
KDR P35968 1/20 0.32
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MGLL Q99685 1/20 0.31
HSD17B10 Q99714 1/20 0.31
BCL2 P10415 1/20 0.31
MCL1 Q07820 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7702973 0.89 MAOA (0.36) MAOAMAOBSLC6A4ALDH1A1HPGD
SCHEMBL245276 0.81 ALDH1A1 (0.43) MAOAMAOBALDH1A1MAPK1MAPT
SCHEMBL11050322 0.78 ALDH1A1 (0.35) ALDH1A1
SCHEMBL195828 0.73 ALDH1A1 (0.59) MAOAMAOBSLC6A4ALDH1A1HPGD
SCHEMBL942072 0.73 ALDH1A1 (0.59) MAOAMAOBSLC6A4ALDH1A1HPGD
SCHEMBL16709768 0.73 ALDH1A1 (0.59) MAOAMAOBSLC6A4ALDH1A1HPGD
SCHEMBL7702876 0.72 MAOA (0.48) MAOAMAOBSLC6A4ALDH1A1HPGD
SCHEMBL23277364 0.71 MAOA (0.62) MAOAMAOBSLC6A4ALDH1A1HPGD
SCHEMBL795030 0.71 MAOA (0.62) MAOAMAOBSLC6A4ALDH1A1HPGD
SCHEMBL3891151 0.71 MAOA (0.62) MAOAMAOBSLC6A4ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1159623-C Radiation-sensitive compsn. of chemical amplification type containing onium salt type photosensitive acid generating agent 克拉瑞特金融(BVI)有限公司 2004-07-28 CN disclosed
US-6358665-B1 ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE CLARIANT INTERNATIONAL LTD. (CH) 2002-03-19 US disclosed
CN-1274433-A Radiation-sensitive compsn. of chemical amplification type containing onium salt type photosensitive acid generating agent CLARIANT INT LTD (CH) 2000-11-22 CN disclosed
EP-1033624-A1 RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE Clariant International Ltd. (CH) 2000-09-06 EP disclosed