SCHEMBL7702973

SCHEMBL7702973

[CH2]CCC[CH]c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.36
MAOB P27338 3/20 0.36
SLC6A4 P31645 1/20 0.35
MMP3 P08254 1/20 0.35
MMP8 P22894 1/20 0.35
MMP13 P45452 1/20 0.35
ALDH1A1 P00352 2/20 0.34
HPGD P15428 1/20 0.34
CHRNA7 P36544 1/20 0.33
HTR2C P28335 1/20 0.32
HTR6 P50406 1/20 0.32
KDR P35968 1/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7708625 0.89 MAOA (0.38) MAOAMAOBSLC6A4MMP3MMP8
SCHEMBL2264621 0.82 ALDH1A1 (0.40) MAOAMAOBALDH1A1MAPK1
SCHEMBL3172024 0.77 ALDH1A1 (0.39) MAOBALDH1A1
SCHEMBL135514 0.75 ALDH1A1 (0.37) MAOBALDH1A1HPGD
SCHEMBL136788 0.75 ALDH1A1 (0.37) MAOBALDH1A1HPGD
SCHEMBL4358420 0.75 ALDH1A1 (0.37) MAOBALDH1A1HPGD
SCHEMBL9122552 0.75 ALDH1A1 (0.37) MAOBALDH1A1HPGD
SCHEMBL8903513 0.75 ALDH1A1 (0.37) MAOBALDH1A1HPGD
SCHEMBL7639550 0.75 ALDH1A1 (0.37) MAOBALDH1A1HPGD
SCHEMBL7702823 0.71 ALDH5A1 (0.44) MAOAMAOBALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1159623-C Radiation-sensitive compsn. of chemical amplification type containing onium salt type photosensitive acid generating agent 克拉瑞特金融(BVI)有限公司 2004-07-28 CN disclosed
US-6358665-B1 ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE CLARIANT INTERNATIONAL LTD. (CH) 2002-03-19 US disclosed
CN-1274433-A Radiation-sensitive compsn. of chemical amplification type containing onium salt type photosensitive acid generating agent CLARIANT INT LTD (CH) 2000-11-22 CN disclosed
EP-1033624-A1 RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE Clariant International Ltd. (CH) 2000-09-06 EP disclosed