SCHEMBL7708636

SCHEMBL7708636

[CH2]CC[CH]c1ccc(N(C)C)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.54
CYP2A13 Q16696 1/20 0.54
APP P05067 4/20 0.47
ALDH1A1 P00352 9/20 0.46
ALOX15 P16050 4/20 0.46
TSHR P16473 3/20 0.46
HSD17B10 Q99714 2/20 0.46
RELA Q04206 1/20 0.45
MAPT P10636 6/20 0.42
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
KDM4E B2RXH2 3/20 0.42
MAPK1 P28482 3/20 0.42
TDP1 Q9NUW8 3/20 0.42
CASP1 P29466 2/20 0.42
HBB P68871 2/20 0.42
THRB P10828 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7708106 0.88 CYP2A6 (0.50) CYP2A6CYP2A13APPALDH1A1ALOX15
SCHEMBL11050322 0.82 ALDH1A1 (0.35) ALDH1A1
SCHEMBL27827550 0.79 CYP2A6 (0.54) CYP2A6CYP2A13APPALDH1A1ALOX15
SCHEMBL7335589 0.78 CYP2A6 (0.62) CYP2A6CYP2A13APPALDH1A1ALOX15
SCHEMBL5469370 0.76 CYP2A6 (0.48) CYP2A6ALDH1A1RELAMAPTKMT2A
SCHEMBL7708200 0.71 HSD17B10 (0.48) CYP2A6TSHRHSD17B10LMNAHTT
SCHEMBL7702901 0.71 ALDH5A1 (0.48) APPALDH1A1ALOX15HSD17B10RELA
SCHEMBL10846378 0.71 APP (0.57) CYP2A6CYP2A13APPALDH1A1ALOX15
SCHEMBL7711381 0.71 CYP1A2 (0.41) TSHRSMN1; SMN2TP53LMNA
SCHEMBL7711464 0.71 ALDH1A1 (0.54) CYP2A6ALDH1A1ALOX15TSHRRELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6358665-B1 ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE CLARIANT INTERNATIONAL LTD. (CH) 2002-03-19 US disclosed
EP-1033624-A1 RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE Clariant International Ltd. (CH) 2000-09-06 EP disclosed