Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6860836 | 0.88 | FFAR4 (0.42) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL7711823 | 0.84 | SIRT1 (0.52) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL7713876 | 0.84 | POLB (0.43) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL7711555 | 0.84 | TSHR (0.39) | — | |
| SCHEMBL6860561 | 0.83 | CASR (0.47) | POLBGAA | |
| SCHEMBL7708679 | 0.83 | CASR (0.47) | POLBGAA | |
| SCHEMBL16823624 | 0.73 | USP2 (0.41) | ALDH1A1KMT2AMEN1MAPTHTT | |
| SCHEMBL7711231 | 0.73 | USP2 (0.41) | ALDH1A1KMT2AMEN1MAPTHTT | |
| SCHEMBL12862879 | 0.72 | HTT (0.45) | ALDH1A1KMT2AMEN1MAPTHTT | |
| SCHEMBL7705256 | 0.72 | GRM2 (0.39) | KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6794385-B2 | ANTITUMOR AGENTS; ANTICANCER AGENTS; OSTEOPOROSIS | PHARMACIA & UPJOHN, S.P.A. (IT) | 2004-09-21 | — | — | US | disclosed |
| US-6794385-B2 | ANTITUMOR AGENTS; ANTICANCER AGENTS; OSTEOPOROSIS | PHARMACIA & UPJOHN, S.P.A. (IT) | 2004-09-21 | — | — | US | disclosed |