Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 11/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7711555 | 0.83 | TSHR (0.39) | GRM2CACNA1GNPC1OPRM1KCNH2 | |
| SCHEMBL7708679 | 0.75 | CASR (0.47) | GRM2NPC1OPRM1KCNH2SIGMAR1 | |
| SCHEMBL6860561 | 0.75 | CASR (0.47) | GRM2NPC1OPRM1KCNH2SIGMAR1 | |
| SCHEMBL7708641 | 0.72 | ALDH1A1 (0.43) | MAPTSMN1; SMN2KMT2A | |
| SCHEMBL7705262 | 0.69 | TSHR (0.47) | MAPTSMN1; SMN2KMT2ATSHR | |
| SCHEMBL7708663 | 0.69 | POLB (0.46) | MAPTSMN1; SMN2KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL6854351 | 0.69 | GRM2 (0.39) | GRM2SIGMAR1 | |
| SCHEMBL7711755 | 0.68 | GAA (0.39) | NPC1MAPTRAB9AKMT2ATSHR | |
| SCHEMBL7711502 | 0.67 | ITGB3 (0.41) | KCNH2SMN1; SMN2KMT2A | |
| SCHEMBL13009737 | 0.65 | OPRK1 (0.48) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6794385-B2 | ANTITUMOR AGENTS; ANTICANCER AGENTS; OSTEOPOROSIS | PHARMACIA & UPJOHN, S.P.A. (IT) | 2004-09-21 | — | — | US | disclosed |
| US-6794385-B2 | ANTITUMOR AGENTS; ANTICANCER AGENTS; OSTEOPOROSIS | PHARMACIA & UPJOHN, S.P.A. (IT) | 2004-09-21 | — | — | US | disclosed |