Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708641 | 0.88 | ALDH1A1 (0.43) | PAX8SIRT2SIRT1ALDH1A1MAPT | |
| SCHEMBL6853881 | 0.82 | SIRT1 (0.53) | FFAR4SIRT2SIRT1ALDH1A1MAPT | |
| SCHEMBL6862489 | 0.82 | POLB (0.47) | FFAR4SIRT2SIRT1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL6854351 | 0.81 | GRM2 (0.39) | ALDH1A1 | |
| SCHEMBL6492849 | 0.72 | ITGB3 (0.50) | FFAR4ALDH1A1MAPTAKR1B1 | |
| SCHEMBL6493305 | 0.72 | ITGB3 (0.50) | FFAR4ALDH1A1MAPTAKR1B1 | |
| SCHEMBL26090227 | 0.72 | PAX8 (0.44) | PAX8ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL18143314 | 0.72 | SIRT1 (0.52) | SIRT2SIRT1ALDH1A1MAPTKMT2A | |
| SCHEMBL16851476 | 0.72 | SIRT1 (0.52) | SIRT2SIRT1ALDH1A1MAPTKMT2A | |
| SCHEMBL7711823 | 0.72 | SIRT1 (0.52) | SIRT2SIRT1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6794385-B2 | ANTITUMOR AGENTS; ANTICANCER AGENTS; OSTEOPOROSIS | PHARMACIA & UPJOHN, S.P.A. (IT) | 2004-09-21 | — | — | US | disclosed |
| US-20030069236-A1 | New benzoxazine derivatives useful as integrin receptor antagonists | PHARMACIA & UPJOHN S.P.A. (IT) | 2003-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069236-A1 | New benzoxazine derivatives useful as integrin receptor antagonists | ITGB1, ITGA1, ITGB3 | FFAR4 217/4885PAX8 4093/4885SIRT2 865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.