Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705235 | 0.87 | CYP2D6 (0.54) | MEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL7711594 | 0.82 | LMNA (0.47) | SLC6A3SLC6A4MEN1LMNAKMT2A | |
| SCHEMBL7711760 | 0.77 | MEN1 (0.39) | SLC6A3SLC6A4MEN1LMNAKMT2A | |
| SCHEMBL7711567 | 0.77 | CHRNA7 (0.44) | MEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL7713731 | 0.76 | ABCB1 (0.42) | MEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL6257638 | 0.76 | CYP2D6 (0.44) | SLC6A4MEN1LMNAKMT2A | |
| SCHEMBL9621424 | 0.76 | SLC6A4 (0.68) | SLC6A3SLC6A4GRIN2DGRIN3BADRA1D | |
| SCHEMBL7711797 | 0.75 | MEN1 (0.48) | MEN1LMNAKMT2ASMN1; SMN2ADRA1A | |
| SCHEMBL7705250 | 0.75 | MEN1 (0.38) | SLC6A4MEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL7713732 | 0.75 | KMT2A (0.38) | SLC6A3SLC6A4MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259493-A2 | SUBSTITUTED PIPERAZINE COMPOUNDS | CV THERAPEUTICS, INC. (US) | 2002-11-27 | — | — | EP | claimed |
| WO-2001062744-A2 | SUBSTITUTED PIPERAZINE COMPOUNDS | CV THERAPEUTICS, INC. (US) | 2001-08-30 | — | — | WO | claimed |
| EP-1259493-A2 | SUBSTITUTED PIPERAZINE COMPOUNDS | CV THERAPEUTICS, INC. (US) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001062744-A2 | SUBSTITUTED PIPERAZINE COMPOUNDS | CV THERAPEUTICS, INC. (US) | 2001-08-30 | — | — | WO | disclosed |