Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6860110 | 0.91 | HDAC1 (0.44) | LMNASMN1; SMN2LTA4HCYP4F2CYP4A11 | |
| SCHEMBL18691961 | 0.84 | MAPK1 (0.47) | LMNASMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL15150399 | 0.83 | LMNA (0.49) | LMNASMN1; SMN2LTA4HCYP4F2CYP4A11 | |
| SCHEMBL7711638 | 0.81 | HDAC6 (0.46) | LMNASMN1; SMN2ALDH1A1HDAC3HDAC4 | |
| SCHEMBL14696969 | 0.79 | LMNA (0.48) | LMNASMN1; SMN2LTA4HNQO2GAA | |
| SCHEMBL28337704 | 0.78 | CYP2D6 (0.47) | LMNASMN1; SMN2ALDH1A1MAPK1KDM4E | |
| SCHEMBL7903528 | 0.77 | HDAC1 (0.62) | HDAC3HDAC4HDAC1HDAC2HDAC6 | |
| SCHEMBL28827514 | 0.76 | LMNA (0.45) | LMNASMN1; SMN2LTA4HGAAMEN1 | |
| SCHEMBL6859239 | 0.76 | FFAR4 (0.46) | SMN1; SMN2ALDH1A1MAPK1HDAC3HDAC4 | |
| SCHEMBL28377221 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2GAAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2978750-B1 | \"SYNTHESIS OF DABIGATRAN\ | USV PRIVATE LTD (IN) | 2020-03-04 | — | — | EP | claimed |
| US-6794385-B2 | ANTITUMOR AGENTS; ANTICANCER AGENTS; OSTEOPOROSIS | PHARMACIA & UPJOHN, S.P.A. (IT) | 2004-09-21 | — | — | US | disclosed |