Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15150399 | 0.81 | LMNA (0.49) | LMNAALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL7708661 | 0.79 | LMNA (0.47) | LMNAALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL7903528 | 0.75 | HDAC1 (0.62) | HDAC3HDAC4HDAC1HDAC2HDAC6 | |
| SCHEMBL14544592 | 0.75 | ALDH1A1 (0.48) | LMNAALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL6860110 | 0.73 | HDAC1 (0.44) | LMNAALDH1A1SMN1; SMN2LTA4HHDAC3 | |
| SCHEMBL14696968 | 0.73 | LMNA (0.44) | LMNAALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL3254096 | 0.72 | LMNA (0.51) | LMNAALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL13833091 | 0.72 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2MAPTMEN1GAA | |
| SCHEMBL1120660 | 0.71 | LMNA (0.50) | LMNAALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL28314875 | 0.71 | NLRP3 (0.41) | LMNASMN1; SMN2GALR3MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013024384-A1 | IMPROVED PROCESS FOR PREPARATION OF DABIGATRAN ETEXILATE AND ITS NOVEL INTERMEDIATE | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2013-02-21 | — | — | WO | disclosed |