Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | UNG | P13051 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708946 | 1.00 | TTR (0.39) | TTRENPP2CYP19A1UNGMYC | |
| SCHEMBL7241306 | 0.82 | MEN1 (0.35) | CYP19A1MYCPTGS1PTGS2MEN1 | |
| SCHEMBL7241309 | 0.82 | MEN1 (0.35) | CYP19A1MYCPTGS1PTGS2MEN1 | |
| SCHEMBL7709322 | 0.81 | CA2 (0.39) | HPGDMRGPRX4KDM4E | |
| SCHEMBL7703338 | 0.81 | FNTA (0.48) | USP2ALDH1A1ALOX15 | |
| SCHEMBL7703335 | 0.81 | FNTA (0.48) | USP2ALDH1A1ALOX15 | |
| SCHEMBL7709317 | 0.81 | CA2 (0.39) | HPGDMRGPRX4KDM4E | |
| SCHEMBL8227733 | 0.80 | KMT2A (0.33) | PTGS1PTGS2KMT2AL3MBTL1MAPT | |
| SCHEMBL7708970 | 0.79 | CYP19A1 (0.47) | CYP19A1POLBTDP1L3MBTL1TBXAS1 | |
| SCHEMBL7245883 | 0.79 | CYP19A1 (0.47) | CYP19A1POLBTDP1L3MBTL1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414145-B1 | TREATING CANCER AND NEUROFIBROMATOSIS | ZENECA LIMITED (GB) | 2002-07-02 | — | — | US | disclosed |