Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.30 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.30 |
| ▸ | S100A10 | P60903 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708940 | 0.71 | MEN1 (0.43) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7714804 | 0.68 | HSD17B10 (0.35) | LMNA | |
| SCHEMBL7385061 | 0.67 | LMNA (0.34) | LMNAL3MBTL1 | |
| SCHEMBL7714547 | 0.66 | — | — | |
| SCHEMBL7386129 | 0.65 | ALOX5 (0.40) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7382853 | 0.65 | MAPT (0.31) | ALDH1A1 | |
| SCHEMBL7378111 | 0.65 | — | — | |
| SCHEMBL7714563 | 0.64 | LMNA (0.32) | LMNA | |
| SCHEMBL7712658 | 0.64 | KMT2A (0.39) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7708977 | 0.64 | TAS1R3 (0.32) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369110-B1 | PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM | SUMITOMO PHARMACEUTICALS COMPANY (JP) | 2002-04-09 | — | — | US | disclosed |
| EP-1083166-A1 | NOVEL SUBSTITUTED GUANIDINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-03-14 | — | — | EP | disclosed |