Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717411 | 0.75 | AR (0.51) | ARKDM4EALDH1A1GLAGAA | |
| SCHEMBL2833045 | 0.63 | DAO (0.53) | DAOKDM4EALDH1A1GLAGAA | |
| SCHEMBL20207784 | 0.59 | AKR1B1 (0.44) | DAOKDM4EALDH1A1HTT | |
| SCHEMBL5716104 | 0.57 | NR3C2 (0.39) | ALDH1A1HTT | |
| SCHEMBL31193836 | 0.57 | AOC1 (0.39) | AR | |
| SCHEMBL1772197 | 0.57 | AR (0.62) | AR | |
| SCHEMBL21324919 | 0.56 | CYP1A2 (0.38) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL6680406 | 0.56 | KDM4E (0.50) | MPOKDM4EALDH1A1GAAMAPT | |
| SCHEMBL4287768 | 0.56 | CA12 (0.41) | ARDAOKDM4EALDH1A1MAPT | |
| SCHEMBL17774951 | 0.56 | HCAR3 (0.35) | MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212303-A2 | BICYCLIC ANDROGEN AND PROGESTERONE RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001016108-A2 | BICYCLIC ANDROGEN AND PROGESTERONE RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2001-03-08 | — | — | WO | disclosed |