Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.43 |
| ▸ | EPOR | P19235 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5719575 | 0.88 | ITGA4 (0.55) | LTA4HITGB1ITGA4 | |
| SCHEMBL6561273 | 0.88 | ITGA4 (0.55) | LTA4HITGB1ITGA4 | |
| Hydrochloric Acid SCHEMBL6509920 | 0.87 | ITGA4 (0.54) | LTA4HITGB1ITGA4 | |
| SCHEMBL26995245 | 0.82 | LTA4H (0.49) | LTA4HSLC7A5TAAR1ALDH1A1 | |
| SCHEMBL26985814 | 0.82 | LTA4H (0.49) | LTA4HSLC7A5TAAR1ALDH1A1 | |
| SCHEMBL2658540 | 0.81 | TAAR1 (0.64) | SLC7A5TAAR1ALDH1A1 | |
| SCHEMBL22458056 | 0.81 | TAAR1 (0.64) | SLC7A5TAAR1ALDH1A1 | |
| SCHEMBL1279049 | 0.81 | TAAR1 (0.64) | SLC7A5TAAR1ALDH1A1 | |
| SCHEMBL23387525 | 0.81 | ITGA4 (0.48) | LTA4HITGB1ITGA4ALDH1A1 | |
| SCHEMBL31070921 | 0.81 | ITGA4 (0.48) | LTA4HITGB1ITGA4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362204-B1 | CONTROLLING IMMUNOLOGY; ANTIINFLAMMATORY AGENTS | CELLTECH THERAPEUTICS, LTD (GB) | 2002-03-26 | — | — | US | disclosed |