SCHEMBL21823972

SCHEMBL21823972

C[Si](C)(C)OC(c1ccccc1)(c1ccccc1)C(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.40
CYP3A4 P08684 2/20 0.40
ALDH1A1 P00352 2/20 0.38
ALOX15 P16050 1/20 0.38
KCNN4 O15554 1/20 0.34
NR1H2 P55055 2/20 0.34
NR1H3 Q13133 2/20 0.34
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C19 P33261 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
CYP2D6 P10635 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
ESR1 P03372 2/20 0.32
ESR2 Q92731 2/20 0.32
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3118068 0.85 MAPK1 (0.42) MAPK1CYP3A4ALDH1A1ALOX15KCNN4
SCHEMBL22188636 0.83 ALDH1A1 (0.38) MAPK1CYP3A4ALDH1A1ALOX15KCNN4
SCHEMBL22188641 0.79 ALDH1A1 (0.34) MAPK1CYP3A4ALDH1A1ALOX15KCNN4
SCHEMBL9474605 0.78 ESR1 (0.53) MAPK1CYP3A4ALDH1A1ALOX15NR1H2
SCHEMBL2856854 0.77 CES1 (0.42) MAPK1CYP3A4ALDH1A1ALOX15KCNN4
SCHEMBL7709329 0.76 KIF11 (0.41) MAPK1ALDH1A1NPC1HPGDRAB9A
SCHEMBL11854971 0.76 KIF11 (0.41) MAPK1ALDH1A1NPC1HPGDRAB9A
SCHEMBL7714437 0.73 KCNN4 (0.42) MAPK1ALDH1A1ALOX15KCNN4
SCHEMBL7714530 0.73 CA4 (0.46) ALDH1A1L3MBTL1KDM4ENPC1RAB9A
SCHEMBL15359072 0.72 ALDH1A1 (0.37) MAPK1CYP3A4ALDH1A1ALOX15KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11953831-B2 Photosensitive composition FUJIFILM CORPORATION (JP) 2024-04-09 US disclosed
CN-115774356-A Liquid crystal sealing agent for liquid crystal dropping method and liquid crystal display panel using same 日本化药株式会社 2023-03-10 CN disclosed
CN-114621722-A Liquid crystal sealant for liquid crystal dropping method 日本化药株式会社 2022-06-14 CN disclosed
CN-114621719-A Liquid crystal sealant for liquid crystal dropping method 日本化药株式会社 2022-06-14 CN disclosed
US-11294280-B2 Coloring composition, cured film, pattern forming method, color filter, solid-state imaging element, and image display device FUJIFILM CORPORATION (JP) 2022-04-05 US disclosed
CN-114058321-A Encapsulant for display 日本化药株式会社 2022-02-18 CN disclosed
CN-107686716-B Liquid crystal sealing agent and liquid crystal display cell using the same 日本化药株式会社 2021-12-24 CN disclosed
CN-107686714-B Liquid crystal sealing agent and liquid crystal display cell using the same 日本化药株式会社 2021-12-10 CN disclosed
CN-111183189-B Colored composition, film, color filter, solid-state imaging element, and image display device 富士胶片株式会社 2021-11-09 CN disclosed
CN-107793954-B Liquid crystal sealing agent and liquid crystal display cell using the same 日本化药株式会社 2021-07-27 CN disclosed
CN-105278177-A Liquid crystal sealant and liquid crystal display unit provided with same NIPPON KAYAKU KK 2016-01-27 CN disclosed
CN-105073800-A Energy ray-curable resin composition and cured product thereof NIPPON KAYAKU KK 2015-11-18 CN disclosed
CN-105073799-A Energy ray-curable resin composition and cured product of same NIPPON KAYAKU KK 2015-11-18 CN disclosed
CN-102612521-B Novel thermal radical generator, method for producing same, liquid crystal sealing agent, and liquid crystal display cell NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2015-10-07 CN disclosed
CN-104789165-A Liquid crystal sealing agent and liquid crystal display cell using same NIPPON KAYAKU KK 2015-07-22 CN disclosed
CN-104789166-A Method for preparing resin composition NIPPON KAYAKU KK 2015-07-22 CN disclosed
CN-104570497-A Liquid crystal sealing agent and liquid crystal display unit using the same NIPPON CHEMICAL KK 2015-04-29 CN disclosed
CN-104516154-A Liquid crystal sealing agent and liquid crystal display cell using same NIPPON KAYAKU KK 2015-04-15 CN disclosed
CN-104031082-A NOVEL THERMAL RADICAL GENERATOR, METHOD FOR PRODUCING THE SAME, LIQUID CRYSTAL SEALING AGENT, AND LIQUID CRYSTAL DISPLAY CELL NIPPON KAYAKU KK 2014-09-10 CN disclosed
CN-102612521-A Novel thermal radical generator, method for producing same, liquid crystal sealing agent, and liquid crystal display cell NIPPON KAYAKU KK 2012-07-25 CN disclosed