Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 7/20 | 0.55 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.55 |
| ▸ | GPR132 | Q9UNW8 | 10/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.52 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.52 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.52 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.49 |
| ▸ | ITGAL | P20701 | 1/20 | 0.49 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706573 | 0.91 | ITGB1 (0.49) | ITGB1ITGA5GPR132ITGA4CMKLR2 | |
| SCHEMBL7607529 | 0.90 | ITGA4 (0.59) | ITGB1ITGA5ITGA4 | |
| SCHEMBL7607352 | 0.82 | ITGA4 (0.55) | ITGB1ITGA5ITGA4 | |
| SCHEMBL7608108 | 0.81 | ITGA4 (0.55) | ITGB1ITGA5ITGA4ITGB7 | |
| SCHEMBL7608992 | 0.81 | ITGA4 (0.69) | ITGB1ITGA5GPR132ITGA4 | |
| SCHEMBL6603278 | 0.79 | ITGB2 (0.48) | ITGB1ITGA5GPR132ITGA4ITGB2 | |
| SCHEMBL6515404 | 0.79 | ITGB1 (0.65) | ITGB1ITGA5ITGA4ITGB7 | |
| SCHEMBL7605825 | 0.78 | ITGB1 (0.59) | ITGB1ITGA5ITGA4ITGB2ICAM1 | |
| SCHEMBL7605822 | 0.78 | ITGB1 (0.59) | ITGB1ITGA5ITGA4ITGB2ICAM1 | |
| SCHEMBL7991508 | 0.78 | ITGB1 (0.59) | ITGB1ITGA5ITGA4ITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362204-B1 | CONTROLLING IMMUNOLOGY; ANTIINFLAMMATORY AGENTS | CELLTECH THERAPEUTICS, LTD (GB) | 2002-03-26 | — | — | US | disclosed |