Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 9/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.45 |
| ▸ | GPR132 | Q9UNW8 | 6/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.42 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608108 | 0.91 | ITGA4 (0.55) | ITGB1ITGA4ITGA5ITGB7RAB9A | |
| SCHEMBL7709504 | 0.91 | ITGB1 (0.55) | ITGB1ITGA4ITGA5GPR132ITGB7 | |
| SCHEMBL7607524 | 0.81 | ITGA4 (0.51) | ITGB1ITGA4ITGA5RAB9A | |
| SCHEMBL7607529 | 0.81 | ITGA4 (0.59) | ITGB1ITGA4ITGA5 | |
| SCHEMBL7485965 | 0.80 | TSHR (0.55) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7612138 | 0.79 | ITGB1 (0.51) | ITGB1ITGA4ITGA5TDP1ITGB7 | |
| SCHEMBL7709191 | 0.76 | LTA4H (0.49) | ITGB1ITGA4 | |
| SCHEMBL7608992 | 0.74 | ITGA4 (0.69) | ITGB1ITGA4ITGA5GPR132 | |
| SCHEMBL14270710 | 0.73 | ITGB1 (0.57) | ITGB1ITGA4ITGA5RAB9A | |
| SCHEMBL7608107 | 0.73 | ITGB1 (0.46) | ITGB1ITGA4TDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362204-B1 | CONTROLLING IMMUNOLOGY; ANTIINFLAMMATORY AGENTS | CELLTECH THERAPEUTICS, LTD (GB) | 2002-03-26 | — | — | US | disclosed |