Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.58 |
| ▸ | NOS2 | P35228 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.52 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16355871 | 0.89 | PTPN1 (0.70) | PTPN1TAAR1TSHRMAPK1NOS2 | |
| SCHEMBL23754156 | 0.89 | PTPN1 (0.70) | PTPN1TAAR1TSHRMAPK1NOS2 | |
| SCHEMBL7715209 | 0.88 | PTPN1 (0.60) | PTPN1TAAR1TSHRMAPK1F2 | |
| SCHEMBL29740697 | 0.85 | PTPN1 (0.79) | PTPN1TAAR1TSHRMAPK1NOS2 | |
| SCHEMBL7769340 | 0.84 | PTPN1 (0.64) | PTPN1TAAR1TSHRMAPK1NOS2 | |
| SCHEMBL8864080 | 0.84 | LTA4H (0.55) | TSHRMAPK1GAAALDH1A1POLB | |
| SCHEMBL29604390 | 0.83 | PTPN1 (0.82) | PTPN1TAAR1TSHRMAPK1NOS2 | |
| SCHEMBL17780116 | 0.83 | PTPN1 (0.82) | PTPN1TAAR1TSHRMAPK1NOS2 | |
| SCHEMBL27779114 | 0.81 | ALOX5 (0.75) | PTPN1TAAR1TSHRMAPK1LMNA | |
| SCHEMBL29105738 | 0.81 | ALOX5 (0.75) | PTPN1TAAR1TSHRMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376524-B1 | ANTIALLERGENS, ANTIHISTAMINES | SUNESIS PHARMACEUTICALS, INC. | 2002-04-23 | — | — | US | disclosed |
| WO-2001098245-A2 | TRIPHENYL COMPOUNDS AS INTERLEUKIN-4 ANTAGONISTS | SUNESIS PHARMACEUTICALS, INC. (US) | 2001-12-27 | — | — | WO | disclosed |