SCHEMBL8864080

SCHEMBL8864080

COc1cc(Oc2ccccc2)ccc1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.55
TUBB4A P04350 1/20 0.53
TUBB P07437 1/20 0.53
TUBA3C P0DPH7 1/20 0.53
TUBA1B P68363 1/20 0.53
TUBA4A P68366 1/20 0.53
TUBB4B P68371 1/20 0.53
TUBB3 Q13509 1/20 0.53
TUBB2A Q13885 1/20 0.53
TUBB8 Q3ZCM7 1/20 0.53
TUBA3E Q6PEY2 1/20 0.53
TUBA1A Q71U36 1/20 0.53
TUBA1C Q9BQE3 1/20 0.53
TUBB6 Q9BUF5 1/20 0.53
TUBB2B Q9BVA1 1/20 0.53
TUBB1 Q9H4B7 1/20 0.53
MAOB P27338 1/20 0.52
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
POLB P06746 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1476982 0.90 MAOB (0.61) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL9623668 0.87 MAOB (0.64) LTA4HTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL5380053 0.86 THRA (0.56) LTA4HMEN1KMT2ANPC1GAA
SCHEMBL5991731 0.86 THRA (0.56) LTA4HMEN1KMT2ANPC1GAA
SCHEMBL7709744 0.84 PTPN1 (0.60) POLBGAAALDH1A1TSHRMAPK1
SCHEMBL11047242 0.83 TUBB4A (0.74) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL8940749 0.83 HDAC4 (0.50) LTA4HTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL11646840 0.82 LTA4H (0.61) LTA4HTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL774501 0.81 THRA (0.52) LTA4HMEN1KMT2AGAAALDH1A1
Methoxymethane SCHEMBL11646837 0.81 LTA4H (0.59) LTA4HTUBB4ATUBBTUBA3CTUBA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5654483-A REACTING ALKOXY-SUBSTITUTED CYCLOHEXANONE WITH DIPHENYLAMINE WHILE FORMING CYCLOHEXANONE FROM ALKOXY-SUBSTITUTED PHENOL IN PRESENCE OF SURFACE-SUPPORTED HYDROGEN TRANSFER CATALYST MITSUI TOATSU CHEMICALS, INC. (JP) 1997-08-05 US disclosed