Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8680676 | 0.84 | ALOX5 (0.61) | ALOX5PTGS2IDO1CALM1ABCB1 | |
| SCHEMBL23748452 | 0.75 | ALOX5 (0.77) | ALOX5PTGS2IDO1CALM1ALDH1A1 | |
| SCHEMBL5657934 | 0.74 | ALOX5 (0.65) | ALOX5PTGS2IDO1CALM1ALDH1A1 | |
| SCHEMBL16088316 | 0.74 | TAAR1 (0.67) | ALOX5PTGS2IDO1CALM1ALDH1A1 | |
| Mequinol SCHEMBL27505839 | 0.74 | ALOX5 (0.73) | ALOX5PTGS2IDO1CALM1ALDH1A1 | |
| SCHEMBL7715224 | 0.73 | PTPN1 (0.71) | ALOX5CALM1ALDH1A1LMNACYP3A4 | |
| SCHEMBL59746 | 0.72 | ALOX5 (0.90) | ALOX5PTGS2IDO1CALM1ALDH1A1 | |
| SCHEMBL29365570 | 0.72 | ALOX5 (0.90) | ALOX5PTGS2IDO1CALM1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL16037890 | 0.72 | IDO1 (0.65) | ALOX5PTGS2IDO1CALM1ALDH1A1 | |
| SCHEMBL28638329 | 0.72 | ESR1 (0.82) | PTGS2ALDH1A1KDM4ELMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376524-B1 | ANTIALLERGENS, ANTIHISTAMINES | SUNESIS PHARMACEUTICALS, INC. | 2002-04-23 | — | — | US | disclosed |
| WO-2001098245-A2 | TRIPHENYL COMPOUNDS AS INTERLEUKIN-4 ANTAGONISTS | SUNESIS PHARMACEUTICALS, INC. (US) | 2001-12-27 | — | — | WO | disclosed |