Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.65 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 7/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7393700 | 0.85 | ALOX5 (0.46) | ALOX5PTGS2IDO1MAPTALDH1A1 | |
| SCHEMBL23748452 | 0.83 | ALOX5 (0.77) | ALOX5PTGS2IDO1MAPTALDH1A1 | |
| SCHEMBL16088316 | 0.81 | TAAR1 (0.67) | ALOX5PTGS2IDO1MAPTALDH1A1 | |
| SCHEMBL6054608 | 0.80 | TAAR1 (0.64) | IDO1MAPTALDH1A1GAACA12 | |
| SCHEMBL59746 | 0.80 | ALOX5 (0.90) | ALOX5PTGS2IDO1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL16037890 | 0.80 | IDO1 (0.65) | ALOX5PTGS2IDO1MAPTALDH1A1 | |
| SCHEMBL29365570 | 0.80 | ALOX5 (0.90) | ALOX5PTGS2IDO1MAPTALDH1A1 | |
| SCHEMBL9049552 | 0.80 | GABRA1 (0.50) | ALOX5PTGS2ALDH1A1HPGDALOX15 | |
| SCHEMBL10501385 | 0.79 | CA12 (0.54) | MAPTALDH1A1KDM4ECYP3A4MAPK1 | |
| SCHEMBL7210177 | 0.79 | ALOX5 (0.87) | ALOX5PTGS2IDO1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294715-B2 | Aporphine and oxoaporphine compounds and pharmaceutical use thereof | LOTUS PHARMACEUTICAL CO., LTD. (TW) | 2007-11-13 | — | — | US | disclosed |
| US-20060211723-A1 | Aporphine and oxoaporphine compounds and pharmaceutical use thereof | LOTUS PHARMACEUTICAL CO., LTD. (TW) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211723-A1 | Aporphine and oxoaporphine compounds and pharmaceutical use thereof | OGFRL1, THOP1, APOL1 | ALOX5 782/4885PTGS2 1378/4885IDO1 503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.