Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 20/20 | 0.83 |
| ▸ | MMP3 | P08254 | 13/20 | 0.83 |
| ▸ | MMP9 | P14780 | 4/20 | 0.83 |
| ▸ | MMP14 | P50281 | 4/20 | 0.83 |
| ▸ | MMP13 | P45452 | 2/20 | 0.83 |
| ▸ | MMP1 | P03956 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7061522 | 1.00 | MMP2 (0.83) | MMP2MMP3MMP9MMP14MMP13 | |
| SCHEMBL6449143 | 1.00 | MMP2 (0.83) | MMP2MMP3MMP9MMP14MMP13 | |
| SCHEMBL6449140 | 0.91 | MMP2 (1.00) | MMP2MMP3MMP9MMP14MMP13 | |
| SCHEMBL7114067 | 0.87 | MMP2 (0.79) | MMP2MMP3MMP9MMP14MMP13 | |
| SCHEMBL6436788 | 0.87 | MMP2 (0.79) | MMP2MMP3MMP9MMP14MMP13 | |
| SCHEMBL7108054 | 0.86 | MMP2 (0.63) | MMP2MMP3MMP9MMP14MMP13 | |
| SCHEMBL7108593 | 0.85 | MMP2 (0.64) | MMP2MMP3MMP9MMP14MMP13 | |
| SCHEMBL6435957 | 0.84 | MMP2 (1.00) | MMP2MMP3MMP9MMP14MMP13 | |
| SCHEMBL7110076 | 0.83 | MMP2 (0.72) | MMP2MMP3MMP9MMP14MMP13 | |
| SCHEMBL7706922 | 0.83 | MMP2 (0.85) | MMP2MMP3MMP9MMP14MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350907-B1 | PEPTIDE ENZYME INHIBITORS | PFIZER INC | 2002-02-26 | — | — | US | disclosed |