Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7707409 | 0.87 | NOS3 (0.32) | NOS1NOS2NOS3 | |
| SCHEMBL7710411 | 0.82 | CYP1A2 (0.39) | CYP1A2LMNAMAPK1HTT | |
| SCHEMBL7712727 | 0.78 | — | — | |
| SCHEMBL4818167 | 0.75 | CYP1A2 (0.41) | CYP1A2LMNAMAPK1HTT | |
| SCHEMBL12368411 | 0.71 | — | — | |
| SCHEMBL11904251 | 0.70 | CYP1A2 (0.48) | CYP1A2LMNAMAPK1HTTNOS1 | |
| SCHEMBL25980968 | 0.68 | CYP1A2 (0.41) | CYP1A2LMNAMAPK1HTTNOS1 | |
| SCHEMBL4871719 | 0.68 | CHRNB2 (0.44) | CYP1A2LMNAMAPK1HTT | |
| SCHEMBL7602107 | 0.66 | CYP1A2 (0.44) | CYP1A2LMNAMAPK1HTTNOS1 | |
| SCHEMBL25268467 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362124-B1 | INCLUDING ORGANOSILICON COMPOUND IN A COORDINATION CATALYST WHICH ALSO CONTAINS; ORGANOMAGNESIUM, ORGANOALUMINUM AND TITANIUM COMPOUNDS; SUPERIOR POLYMERIZATION ACTIVITY AND STEREOSPECIFIC EFFICIENCY. | SUMITOMO CHEMICAL CO., LTD. (JP) | 2002-03-26 | — | — | US | disclosed |