Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.30 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5854091 | 0.76 | LMNA (0.33) | LMNAKMT2AITGB1ITGA4ITGB7 | |
| Hydrochloric Acid SCHEMBL5855320 | 0.75 | ITGB1 (0.33) | LMNAKMT2AITGB1ITGA4ITGB7 | |
| Hydrochloric Acid SCHEMBL5853909 | 0.74 | LMNA (0.32) | LMNAKMT2AITGB1ITGA4ITGB7 | |
| Hydrochloric Acid SCHEMBL5855094 | 0.70 | LMNA (0.35) | LMNAKMT2AITGB1ITGA4ITGB7 | |
| Hydrochloric Acid SCHEMBL5852677 | 0.69 | LMNA (0.34) | LMNAKMT2AITGB1ITGA4ITGB7 | |
| Hydrochloric Acid SCHEMBL5854580 | 0.69 | KCNK3 (0.38) | LMNAKMT2AKCNK3KCNK9 | |
| Hydrochloric Acid SCHEMBL5853440 | 0.68 | LMNA (0.34) | LMNAKMT2AITGB1ITGA4ITGB7 | |
| Hydrochloric Acid SCHEMBL6908382 | 0.66 | FAAH (0.31) | LMNA | |
| Hydrochloric Acid SCHEMBL5854332 | 0.65 | KCNK3 (0.36) | LMNAKMT2AKCNK3KCNK9 | |
| Hydrochloric Acid SCHEMBL5853413 | 0.65 | KCNK3 (0.36) | LMNAKMT2AKCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376416-B1 | COORDINATION POLYMERIZATION CATALYSTS | JAPAN POLYCHEM CORPORATION (JP) | 2002-04-23 | — | — | US | disclosed |