Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 5/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | CALML3 | P27482 | 1/20 | 0.55 |
| ▸ | SDHA | P31040 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 6/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10753981 | 0.89 | F10 (0.57) | ABCB11MAOAMAOBLMNAPTGS1 | |
| SCHEMBL10752537 | 0.88 | ABCB11 (0.58) | ABCB11MAOAMAOBLMNAPTGS1 | |
| Dup-721 SCHEMBL9521400 | 0.88 | ABCB11 (0.59) | ABCB11MAOAMAOBLMNAPTGS1 | |
| Dup-721 SCHEMBL4402113 | 0.88 | ABCB11 (0.59) | ABCB11MAOAMAOBLMNAPTGS1 | |
| SCHEMBL10758941 | 0.87 | ABCB11 (0.57) | ABCB11MAOAMAOBLMNAPTGS1 | |
| SCHEMBL10752006 | 0.86 | ABCB11 (0.54) | ABCB11MAOAMAOBLMNAPTGS1 | |
| SCHEMBL18770274 | 0.85 | MAOA (0.59) | ABCB11MAOAMAOBLMNAPTGS1 | |
| SCHEMBL6098308 | 0.85 | MAOA (0.59) | ABCB11MAOAMAOBLMNAPTGS1 | |
| SCHEMBL13298924 | 0.85 | MAOA (0.61) | ABCB11MAOAMAOBLMNAPTGS1 | |
| SCHEMBL9550268 | 0.85 | ABCB11 (0.56) | ABCB11MAOAMAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362191-B1 | ANTIBIOTICS | ZENECA LTD. (GB) | 2002-03-26 | — | — | US | disclosed |
| EP-1007525-A1 | AMINOMETYL OXOOXAZOLIDINYL BENZENE DERIVATIVES | ZENECA LIMITED (GB) | 2000-06-14 | — | — | EP | disclosed |
| WO-1999011642-A1 | AMINOMETYL OXOOXAZOLIDINYL BENZENE DERIVATIVES | ZENECA LIMITED (GB) | 1999-03-11 | — | — | WO | disclosed |