Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710699 | 0.83 | ITGB1 (0.45) | APP | |
| SCHEMBL7714197 | 0.82 | ITGB1 (0.36) | AKR1B1ALOX5PTGESFFAR1MAPT | |
| SCHEMBL7714160 | 0.82 | AKR1B1 (0.32) | AKR1B1ALOX5PTGESFFAR1RAB9A | |
| SCHEMBL7710675 | 0.79 | ELANE (0.40) | APPMEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL7710671 | 0.79 | ELANE (0.40) | APPMEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL7710677 | 0.77 | KMT2A (0.34) | FFAR1KMT2AMAPTPPARGKDM4E | |
| SCHEMBL7718424 | 0.71 | ACACB (0.31) | AKR1B1FFAR1 | |
| SCHEMBL7718449 | 0.68 | ITGB1 (0.64) | PPARG | |
| SCHEMBL10975511 | 0.68 | PPARA (0.55) | PPARG | |
| SCHEMBL7718445 | 0.67 | ACE (0.53) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |