Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714160 | 0.87 | AKR1B1 (0.32) | AKR1B1PTGESALOX5FFAR1 | |
| SCHEMBL7264060 | 0.84 | ITGB1 (0.55) | ITGB1ITGA4 | |
| SCHEMBL7710672 | 0.82 | AKR1B1 (0.34) | AKR1B1KDM4EGAAPTGESALOX5 | |
| SCHEMBL7714195 | 0.81 | ITGB1 (0.46) | ITGB1ITGA4MAPT | |
| SCHEMBL7714199 | 0.81 | ITGB1 (0.46) | ITGB1ITGA4MAPT | |
| SCHEMBL7714203 | 0.78 | HPGD (0.36) | ITGB1ITGA4CSF1RHPGDALDH1A1 | |
| SCHEMBL7718424 | 0.76 | ACACB (0.31) | AKR1B1ACACBFFAR1 | |
| SCHEMBL7718457 | 0.76 | ITGA4 (0.56) | ITGB1ITGA4HPGDNPSR1 | |
| SCHEMBL7710729 | 0.73 | SLC2A1 (0.36) | ITGB1ITGA4TSHRHPGDALDH1A1 | |
| SCHEMBL7265041 | 0.72 | ITGB1 (0.44) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |