Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 2/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 6/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714164 | 0.84 | ACACB (0.34) | KMT2ATOP2ATOP2BACACBACACA | |
| SCHEMBL7714203 | 0.84 | HPGD (0.36) | PPARGALOX5APALDH1A1LMNAMAPT | |
| SCHEMBL7710699 | 0.82 | ITGB1 (0.45) | — | |
| SCHEMBL7710671 | 0.79 | ELANE (0.40) | KMT2APPARGPPARAALDH1A1LMNA | |
| SCHEMBL7710675 | 0.79 | ELANE (0.40) | KMT2APPARGPPARAALDH1A1LMNA | |
| SCHEMBL7710672 | 0.77 | AKR1B1 (0.34) | KMT2APPARGFFAR1KDM4EMAPT | |
| SCHEMBL7718431 | 0.74 | SLC8A1 (0.33) | PPARG | |
| SCHEMBL7716478 | 0.73 | KDM4E (0.33) | KMT2APPARGP2RX3KDM4EALDH1A1 | |
| SCHEMBL7718445 | 0.71 | ACE (0.53) | PPARGPPARA | |
| SCHEMBL7718449 | 0.68 | ITGB1 (0.64) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |