Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710675 | 1.00 | ELANE (0.40) | ELANEMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7710695 | 0.92 | ITGB1 (0.45) | ITGB1ITGA4APP | |
| SCHEMBL7710699 | 0.92 | ITGB1 (0.45) | ITGB1ITGA4APP | |
| SCHEMBL7716190 | 0.85 | ITGB1 (0.54) | ELANEMEN1KMT2AITGB1ITGA4 | |
| SCHEMBL7714199 | 0.83 | ITGB1 (0.46) | ELANEITGB1ITGA4PARP1PARP3 | |
| SCHEMBL7714162 | 0.83 | ELANE (0.37) | ELANEITGB1ITGA4TACR3PARP1 | |
| SCHEMBL7714195 | 0.83 | ITGB1 (0.46) | ELANEITGB1ITGA4PARP1PARP3 | |
| SCHEMBL7714158 | 0.83 | ELANE (0.37) | ELANEITGB1ITGA4TACR3PARP1 | |
| SCHEMBL7710677 | 0.79 | KMT2A (0.34) | KMT2AALDH1A1LMNAPPARGPPARA | |
| SCHEMBL7710672 | 0.79 | AKR1B1 (0.34) | MEN1KMT2APPARGMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |