Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.33 |
| ▸ | SELE | P16581 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710683 | 0.80 | ITGB1 (0.36) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL7710681 | 0.80 | ITGB1 (0.36) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL7716187 | 0.80 | MAPT (0.35) | MEN1KMT2AMAPT | |
| SCHEMBL7716184 | 0.80 | MAPT (0.35) | MEN1KMT2AMAPT | |
| SCHEMBL7716183 | 0.78 | MAPT (0.37) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL7259054 | 0.73 | ITGB1 (0.33) | MAPT | |
| SCHEMBL7710690 | 0.71 | ATM (0.39) | ATMMAPTPOLBSLC2A1RAD52 | |
| SCHEMBL7710734 | 0.70 | SLC2A1 (0.41) | ALDH1A1KMT2AATMMAPTHSD17B10 | |
| SCHEMBL7263379 | 0.70 | ITGB1 (0.43) | — | |
| SCHEMBL7716447 | 0.68 | ITGB1 (0.63) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |