Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.34 |
| ▸ | SELE | P16581 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710681 | 1.00 | ITGB1 (0.36) | ITGB1ITGA4TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL7263379 | 0.81 | ITGB1 (0.43) | ITGB1ITGA4 | |
| SCHEMBL7710685 | 0.80 | ALDH1A1 (0.34) | ALDH1A1KDM4EMAPTRXFP1ICAM1 | |
| SCHEMBL7710690 | 0.80 | ATM (0.39) | ITGB1ITGA4MAPTPTGDRPOLB | |
| SCHEMBL7716175 | 0.79 | P2RX3 (0.36) | ITGB1ITGA4MAPTELANEMEN1 | |
| SCHEMBL7716447 | 0.78 | ITGB1 (0.63) | ITGB1ITGA4PTGDR | |
| SCHEMBL7716179 | 0.77 | ELANE (0.40) | ITGB1ITGA4ALDH1A1KDM4EMAPT | |
| SCHEMBL7716169 | 0.77 | ELANE (0.40) | ITGB1ITGA4ALDH1A1KDM4EMAPT | |
| SCHEMBL7716453 | 0.76 | ITGB1 (0.43) | ITGB1ITGA4PTGDRKMT2A | |
| SCHEMBL7716445 | 0.76 | ITGB1 (0.43) | ITGB1ITGA4PTGDRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |