SCHEMBL771074

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL771352	0.89	HSD11B1 (0.52)	HSD11B1EPHX2EPHX1DPP4
	SCHEMBL770823	0.88	EPHX2 (0.53)	HSD11B1EPHX2EPHX1
	SCHEMBL770368	0.86	EPHX2 (0.58)	EPHX2EPHX1
	SCHEMBL770515	0.82	EPHX2 (0.56)	HSD11B1EPHX2EPHX1
	SCHEMBL786852	0.81	HSD11B1 (0.53)	HSD11B1EPHX2EPHX1
	SCHEMBL771489	0.78	EPHX2 (0.56)	HSD11B1EPHX2EPHX1
	SCHEMBL771026	0.77	PRMT3 (0.41)	HSD11B1EPHX2
	SCHEMBL770226	0.76	PRMT3 (0.40)	HSD11B1EPHX2DPP4
	SCHEMBL771005	0.76	EPHX2 (0.50)	EPHX2EPHX1
	SCHEMBL772690	0.76	EPHX2 (0.50)	EPHX2EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.